Design-assist of a 214,000 sf lab/office project with GMP warehouse and a full cafeteria. In addition to the common lab services, this project included GMP clean areas, a WFI system, clean steam, a validated purified water system, LN2, industrial waste treatment, and extensive monitoring of owner equipment. The entire project was designed and built in less than 12 months, requiring the highest level of integration between the design and construction teams to allow construction to progress while design was ongoing.
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Design-assist of a large 3-story biotech tenant improvement. The research facility includes a conference center, a 25,000 sq. ft. 2-story vivarium, 40,000 sq. ft. of biology labs, 45,000 sq. ft. of chemistry labs, and 53,000 sq. ft. of general research and development, administrative offices, and a fitness center. Scope included HVAC, plumbing, and process for the building and a central plant.
Ionis Pharmaceuticals (formerly Isis Pharmaceuticals) was a ground up, new construction of a 170, 838 sq. ft., 2-story corporate headquarters which included labs, vivarium, research spaces, administrative spaces, conference rooms, seminar and board room facilities. This design-assist project includes drought-tolerant landscaping, water features utilizing recycled water, outdoor dining and meeting spaces and a sports court for employee use. The building’s sustainable features will make it eligible for certification by the U.S. Green Building Council. The project scope included HVAC, plumbing and process piping consisting of a 1, 200-ton VPF central plant, seven-chemical solvent delivery/waste system and a 16, 000 sq. ft. vivarium. Solvent delivery/waste system includes approximately 2, 000 linear-feet of orbitally welded stainless steel piping, central solvent delivery, pumped waste recovery to central collection and complete instrumentation & automation system. This fast-track project was ready for occupancy 48 weeks after beginning site excavation.
Start / Completion Date: April 2009 / December 2010
The City of Hope Central Chiller Upgrade project featured the largest absorption chiller west of Texas at the time of installation. Weighing over 130, 000 lbs., it is rated for 2000 tons of chilled water capacity. This project was a mechanical prime delivery method in which all subcontractors were managed by Pacific Rim Mechanical. Our scope included cutting an opening in the side of the masonry wall to install the behemoth chiller into the structure. Existing slabs were removed and new foundations were set. Large piping support structures were built and chilled and condenser water up to 24” diameter were installed. This project was administered by OSHPD.
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Start / Completion Date: September 2010 / April 2012 The scope included: Process and environmental chilled water/heating hot waterPiping systems include copper, carbon steel, stainless steel and PVC. Our controls team installed open architecture controls on both process and environmental systems.
The centerpiece is a 90-ton cyclotron, a machine that accelerates protons to 70% of the speed of light creating a beam that can reach tumors that are up to 14 inches deep.
The most unique aspect of this project is that through super-cooling of the cyclotron core (to about 3° Kelvin) the power draw is reduced to a fraction of that of similar facilities. The beam can also be shaped in three dimensions to avoid harming surrounding healthy tissues, targeting tumors with unprecedented accuracy
Illumina’s new World Headquarters was an entire campus project consisting of major renovation of three buildings and a new 4-story tower. The 450, 000 sq. ft., design-assist project included labs, an extensive Solvent Delivery System, research spaces, administrative spaces, conference rooms, seminar and board room facilities and an upgrade to an existing central plant to accommodate the expansion.
The scope included HVAC (including air handling units), plumbing, complete hot water Hydronic System, and high purity process piping system for a chemical solvent delivery system for their heart of the research. Solvent delivery system included approximately 2, 700 linear-feet of orbitally welded clean for oxygen stainless steel piping, 4, 000 gallon stainless steel waste holding tank with complete instrumentation and automation system. The central plant building included an addition of a 800-ton centrifugal chiller with pumps and a cooling tower with a filtration skid.